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    "generado": "2026-10-18T00:31:12+00:00",
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        {
            "id": "sindrome-ckm",
            "titulo": "Síndrome cardiovascular-renal-metabólico (CKM): qué es",
            "resumen": "Por qué la salud del corazón, los riñones y el metabolismo se cuida en conjunto, cómo se detecta el síndrome CKM y qué se puede hacer, según la guía 2026.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/sindrome-ckm",
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                "dieta",
                "actividad-fisica",
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                "imc",
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                1,
                2,
                3,
                4
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            "fuentes": [
                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                },
                {
                    "cita": "Ndumele CE, et al. Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association. Circulation. 2023;148:1606–1635.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001184"
                },
                {
                    "cita": "Lloyd-Jones DM, et al. Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health. Circulation. 2022;146:e18–e43.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001078"
                }
            ],
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                "estado": "pendiente",
                "equipo": "Equipo médico de Segunda Opinión Médica"
            },
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        },
        {
            "id": "estadios-ckm",
            "titulo": "Estadíos del síndrome CKM: del 0 al 4",
            "resumen": "Los criterios de cada estadío del síndrome cardiovascular-renal-metabólico según la guía AHA/ACC/ADA/ASN 2026, y cada cuánto controlarse.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/estadios-ckm",
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                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                },
                {
                    "cita": "KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int. 2024;105(4S):S117–S314.",
                    "url": "https://doi.org/10.1016/j.kint.2023.10.018"
                },
                {
                    "cita": "Khan SS, et al. Development and Validation of the American Heart Association's PREVENT Equations. Circulation. 2024;149:430–449.",
                    "url": "https://doi.org/10.1161/CIRCULATIONAHA.123.067626"
                }
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            },
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        {
            "id": "prevent-riesgo-cardiovascular",
            "titulo": "Ecuaciones PREVENT: tu riesgo cardiovascular a 10 y 30 años",
            "resumen": "Qué calculan las ecuaciones PREVENT de la AHA, qué datos usan y cómo la guía CKM 2026 usa sus resultados para decidir tratamientos.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/prevent-riesgo-cardiovascular",
            "tipo": "ckm",
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                {
                    "cita": "Khan SS, et al. Development and Validation of the American Heart Association's PREVENT Equations. Circulation. 2024;149:430–449.",
                    "url": "https://doi.org/10.1161/CIRCULATIONAHA.123.067626"
                },
                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                }
            ],
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                "estado": "pendiente",
                "equipo": "Equipo médico de Segunda Opinión Médica"
            },
            "actualizado": "2026-10-01"
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        {
            "id": "hipertension",
            "titulo": "Hipertensión arterial",
            "resumen": "Cuándo la presión es alta, cómo medirla bien en casa y qué se puede hacer, con los criterios de la AHA/ACC y de la guía CKM 2026.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/hipertension",
            "tipo": "condicion",
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                "dieta",
                "actividad-fisica",
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                3,
                4
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                "55284-4",
                "82290-8",
                "39156-5"
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                {
                    "cita": "Whelton PK, et al. 2017 ACC/AHA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. Hypertension. 2018;71:e13–e115.",
                    "url": "https://doi.org/10.1161/HYP.0000000000000065"
                },
                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                },
                {
                    "cita": "Sacks FM, et al. Effects on Blood Pressure of Reduced Dietary Sodium and the Dietary Approaches to Stop Hypertension (DASH) Diet. N Engl J Med. 2001;344:3–10.",
                    "url": "https://doi.org/10.1056/NEJM200101043440101"
                },
                {
                    "cita": "Lloyd-Jones DM, et al. Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health. Circulation. 2022;146:e18–e43.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001078"
                }
            ],
            "revision": {
                "estado": "pendiente",
                "equipo": "Equipo médico de Segunda Opinión Médica"
            },
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        },
        {
            "id": "colesterol-y-trigliceridos",
            "titulo": "Colesterol y triglicéridos",
            "resumen": "Qué significan el colesterol LDL, el HDL, el no HDL, los triglicéridos y la lipoproteína(a), y cómo se decide el tratamiento.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/colesterol-y-trigliceridos",
            "tipo": "condicion",
            "idioma": "es-AR",
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                2,
                3,
                4
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                "43396-1",
                "82290-8"
            ],
            "fuentes": [
                {
                    "cita": "Grundy SM, et al. 2018 AHA/ACC Guideline on the Management of Blood Cholesterol. Circulation. 2019;139:e1082–e1143.",
                    "url": "https://doi.org/10.1161/CIR.0000000000000625"
                },
                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                },
                {
                    "cita": "Lloyd-Jones DM, et al. Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health. Circulation. 2022;146:e18–e43.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001078"
                }
            ],
            "revision": {
                "estado": "pendiente",
                "equipo": "Equipo médico de Segunda Opinión Médica"
            },
            "actualizado": "2026-10-01"
        },
        {
            "id": "prediabetes-y-diabetes-tipo-2",
            "titulo": "Prediabetes y diabetes tipo 2",
            "resumen": "Cómo se diagnostican la prediabetes y la diabetes tipo 2, qué lugar ocupan en el síndrome CKM y qué se puede hacer para prevenirlas y tratarlas.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/prediabetes-y-diabetes-tipo-2",
            "tipo": "condicion",
            "idioma": "es-AR",
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                "glucosa",
                "dieta",
                "actividad-fisica",
                "imc"
            ],
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                1,
                2,
                3,
                4
            ],
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                "4548-4",
                "82290-8",
                "39156-5"
            ],
            "fuentes": [
                {
                    "cita": "American Diabetes Association Professional Practice Committee. 2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes—2025. Diabetes Care. 2025;48(Supl. 1).",
                    "url": "https://diabetesjournals.org/care/issue/48/Supplement_1"
                },
                {
                    "cita": "Diabetes Prevention Program Research Group; Knowler WC, et al. Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin. N Engl J Med. 2002;346:393–403.",
                    "url": "https://doi.org/10.1056/NEJMoa012512"
                },
                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                },
                {
                    "cita": "Lloyd-Jones DM, et al. Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health. Circulation. 2022;146:e18–e43.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001078"
                }
            ],
            "revision": {
                "estado": "pendiente",
                "equipo": "Equipo médico de Segunda Opinión Médica"
            },
            "actualizado": "2026-10-01"
        },
        {
            "id": "obesidad-y-grasa-abdominal",
            "titulo": "Sobrepeso, obesidad y grasa abdominal",
            "resumen": "Por qué el exceso de grasa, sobre todo la abdominal, es el punto de partida del síndrome CKM, cómo se mide y qué tratamientos tienen evidencia.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/obesidad-y-grasa-abdominal",
            "tipo": "condicion",
            "idioma": "es-AR",
            "le8": [
                "imc",
                "dieta",
                "actividad-fisica",
                "sueno"
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                1,
                2,
                3,
                4
            ],
            "loinc": [
                "39156-5",
                "82290-8",
                "93832-4"
            ],
            "fuentes": [
                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                },
                {
                    "cita": "Jensen MD, et al. 2013 AHA/ACC/TOS Guideline for the Management of Overweight and Obesity in Adults. Circulation. 2014;129(25 Supl. 2):S102–S138.",
                    "url": "https://doi.org/10.1161/01.cir.0000437739.71477.ee"
                },
                {
                    "cita": "Lincoff AM, et al. Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT). N Engl J Med. 2023;389:2221–2232.",
                    "url": "https://doi.org/10.1056/NEJMoa2307563"
                },
                {
                    "cita": "Lloyd-Jones DM, et al. Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health. Circulation. 2022;146:e18–e43.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001078"
                }
            ],
            "revision": {
                "estado": "pendiente",
                "equipo": "Equipo médico de Segunda Opinión Médica"
            },
            "actualizado": "2026-10-01"
        },
        {
            "id": "enfermedad-renal-cronica",
            "titulo": "Enfermedad renal crónica",
            "resumen": "Cómo se detecta la enfermedad renal crónica con dos análisis simples, qué significan las categorías KDIGO y cómo se protege el riñón.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/enfermedad-renal-cronica",
            "tipo": "condicion",
            "idioma": "es-AR",
            "le8": [
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                4
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            "loinc": [
                "55284-4",
                "4548-4"
            ],
            "fuentes": [
                {
                    "cita": "KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney Int. 2024;105(4S):S117–S314.",
                    "url": "https://doi.org/10.1016/j.kint.2023.10.018"
                },
                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                }
            ],
            "revision": {
                "estado": "pendiente",
                "equipo": "Equipo médico de Segunda Opinión Médica"
            },
            "actualizado": "2026-10-01"
        },
        {
            "id": "insuficiencia-cardiaca",
            "titulo": "Insuficiencia cardíaca y pre-insuficiencia cardíaca",
            "resumen": "Los estadíos de la insuficiencia cardíaca, cómo se detecta la pre-insuficiencia antes de los síntomas y qué tratamientos cambian el pronóstico.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/insuficiencia-cardiaca",
            "tipo": "condicion",
            "idioma": "es-AR",
            "le8": [
                "presion",
                "glucosa",
                "imc"
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            "ckm": [
                3,
                4
            ],
            "loinc": [
                "55284-4",
                "4548-4",
                "39156-5"
            ],
            "fuentes": [
                {
                    "cita": "Heidenreich PA, et al. 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure. Circulation. 2022;145:e895–e1032.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001063"
                },
                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                },
                {
                    "cita": "Khan SS, et al. Development and Validation of the American Heart Association's PREVENT Equations. Circulation. 2024;149:430–449.",
                    "url": "https://doi.org/10.1161/CIRCULATIONAHA.123.067626"
                }
            ],
            "revision": {
                "estado": "pendiente",
                "equipo": "Equipo médico de Segunda Opinión Médica"
            },
            "actualizado": "2026-10-01"
        },
        {
            "id": "enfermedad-coronaria",
            "titulo": "Enfermedad coronaria e infarto",
            "resumen": "Qué es la enfermedad coronaria, cómo reconocer un infarto, cómo se detecta la aterosclerosis antes de los síntomas y qué tratamientos tienen evidencia.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/enfermedad-coronaria",
            "tipo": "condicion",
            "idioma": "es-AR",
            "le8": [
                "colesterol",
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                4
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                "43396-1",
                "55284-4",
                "72166-2",
                "4548-4"
            ],
            "fuentes": [
                {
                    "cita": "Virani SS, et al. 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease. Circulation. 2023;148:e9–e119.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001168"
                },
                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                },
                {
                    "cita": "Grundy SM, et al. 2018 AHA/ACC Guideline on the Management of Blood Cholesterol. Circulation. 2019;139:e1082–e1143.",
                    "url": "https://doi.org/10.1161/CIR.0000000000000625"
                }
            ],
            "revision": {
                "estado": "pendiente",
                "equipo": "Equipo médico de Segunda Opinión Médica"
            },
            "actualizado": "2026-10-01"
        },
        {
            "id": "fibrilacion-auricular-y-acv",
            "titulo": "Fibrilación auricular y ACV",
            "resumen": "Cómo se relacionan la fibrilación auricular y el ACV, cómo reconocer un ACV a tiempo y qué se puede hacer para prevenirlos.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/fibrilacion-auricular-y-acv",
            "tipo": "condicion",
            "idioma": "es-AR",
            "le8": [
                "presion",
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                2,
                3,
                4
            ],
            "loinc": [
                "55284-4",
                "72166-2",
                "93832-4",
                "39156-5"
            ],
            "fuentes": [
                {
                    "cita": "Joglar JA, et al. 2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation. Circulation. 2024;149:e1–e156.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001193"
                },
                {
                    "cita": "Bushnell C, et al. 2024 Guideline for the Primary Prevention of Stroke: A Guideline From the American Heart Association/American Stroke Association. Stroke. 2024;55:e344–e424.",
                    "url": "https://doi.org/10.1161/STR.0000000000000475"
                },
                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                }
            ],
            "revision": {
                "estado": "pendiente",
                "equipo": "Equipo médico de Segunda Opinión Médica"
            },
            "actualizado": "2026-10-01"
        },
        {
            "id": "plan-bienestar-100-dias",
            "titulo": "Plan Bienestar 100 Días®",
            "resumen": "El programa de Segunda Opinión Médica para mejorar tu salud cardiovascular, renal y metabólica en 100 días: consultas, evaluaciones y seguimiento según tu estadío CKM.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/plan-bienestar-100-dias",
            "tipo": "programa",
            "idioma": "es-AR",
            "le8": [
                "dieta",
                "actividad-fisica",
                "nicotina",
                "sueno",
                "imc",
                "colesterol",
                "glucosa",
                "presion"
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                0,
                1,
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            "loinc": [
                "82290-8",
                "72166-2",
                "93832-4",
                "39156-5",
                "43396-1",
                "4548-4",
                "55284-4"
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            "fuentes": [
                {
                    "cita": "Ndumele CE, Rodriguez F, et al. 2026 AHA/ACC/ADA/ASN Guideline for the Prevention, Detection, Evaluation, and Management of Cardiovascular-Kidney-Metabolic Syndrome. Circulation. 2026.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001453"
                },
                {
                    "cita": "Lloyd-Jones DM, et al. Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health. Circulation. 2022;146:e18–e43.",
                    "url": "https://doi.org/10.1161/CIR.0000000000001078"
                },
                {
                    "cita": "Catálogo de alertas y derivaciones del Plan Bienestar 100 Días® por estadío CKM, firmado por los Dres. Alejandro Barbagelata y Alejandro Sergio D'Alessandro (27/09/2026).",
                    "url": ""
                }
            ],
            "revision": {
                "estado": "pendiente",
                "equipo": "Equipo médico de Segunda Opinión Médica"
            },
            "actualizado": "2026-10-01"
        },
        {
            "id": "suplementos-vitaminas-y-antioxidantes",
            "titulo": "Suplementos de vitaminas, minerales y antioxidantes: ¿protegen el corazón?",
            "resumen": "Qué muestran los grandes estudios sobre vitaminas, antioxidantes, omega-3 y otros suplementos para prevenir infartos y ACV.",
            "url": "https://contenidos.segundaopinionmedica.org/biblioteca/suplementos-vitaminas-y-antioxidantes",
            "tipo": "evidencia",
            "idioma": "es-AR",
            "le8": [
                "dieta"
            ],
            "ckm": [
                0,
                1,
                2,
                3,
                4
            ],
            "loinc": [],
            "fuentes": [
                {
                    "cita": "US Preventive Services Task Force; Mangione CM, et al. Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer. JAMA. 2022;327(23):2326–2333.",
                    "url": "https://doi.org/10.1001/jama.2022.8970"
                },
                {
                    "cita": "Manson JE, et al. Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease (VITAL). N Engl J Med. 2019;380:33–44.",
                    "url": "https://doi.org/10.1056/NEJMoa1809944"
                },
                {
                    "cita": "Manson JE, et al. Marine n−3 Fatty Acids and Prevention of Cardiovascular Disease and Cancer (VITAL). N Engl J Med. 2019;380:23–32.",
                    "url": "https://doi.org/10.1056/NEJMoa1811403"
                },
                {
                    "cita": "Siscovick DS, et al. Omega-3 Polyunsaturated Fatty Acid (Fish Oil) Supplementation and the Prevention of Clinical Cardiovascular Disease: A Science Advisory From the American Heart Association. Circulation. 2017;135:e867–e884.",
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                    "cita": "Estruch R, et al. Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts (PREDIMED). N Engl J Med. 2018;378:e34.",
                    "url": "https://doi.org/10.1056/NEJMoa1800389"
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                    "cita": "American Diabetes Association Professional Practice Committee. 5. Facilitating Positive Health Behaviors and Well-being to Improve Health Outcomes: Standards of Care in Diabetes—2025. Diabetes Care. 2025;48(Supl. 1).",
                    "url": "https://diabetesjournals.org/care/issue/48/Supplement_1"
                },
                {
                    "cita": "IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Some Drugs and Herbal Products. IARC Monographs, Vol. 108. Lyon: IARC; 2016.",
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        {
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}